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DOI: 10.1007/s00441-019-03016-8

At the receptor level, BPC-157 interacts with the growth hormone receptor pathway, activating downstream JAK2-STAT signaling that contributes to its regenerative profile

From Rat Studies to Human Extrapolation From rat studies, the remarkably consistent effective dose range of 0.0045 mg/lb to 0.0000045 mg/lb intraperitoneally (a 1000-fold range showing similar efficacy) worked across depression, anxiety, Parkinsons, stroke, schizophrenia, and seizure models